@charset "UTF-8";
/* updates 2021 Dec */
.mw-md {
  max-width: 900px;
  padding: 0 10px;
  margin: auto;
}

.home {
  padding: 66px 0;
}

.home .title {
  color: #000000;
  font-size: 35px;
  font-weight: bold;
  letter-spacing: 0;
  line-height: 40px;
  text-align: center;
}

.font-red {
  color: #b93a34;
}

.home .sub-title {
  color: #000000;
  font-size: 17.6px;
  letter-spacing: 0;
  line-height: 24.2px;
  text-align: center;
  max-width: 590px;
  margin: 7px auto 50px;
}

.category {
  display: block;
  margin: 0px 10px;
}

/* .category--img {
  max-width: 380px;
} */
.category--title {
  color: #b93a34;
  font-size: 40px;
  font-weight: bold;
  letter-spacing: 0;
  line-height: 30px;
  text-align: center;
  margin-top: 27px;
}

.category--subTitle {
  color: #000000;
  font-size: 16px;
  font-weight: bold;
  letter-spacing: 0;
  line-height: 20px;
  text-align: center;
  margin-top: 17px;
}

.navbar {
  display: flex;
  justify-content: flex-end;
  align-items: center;
  padding-right: 10%;
  height: 123px;
}

body[data-fontsize=md] .navbar {
  height: 154px;
}

body[data-fontsize=lg] .navbar {
  height: 154px;
}

.nav-link {
  margin-top: -14px;
}

.nav-link {
  color: #000000;
  font-size: 18px;
  font-weight: 600;
  letter-spacing: 0;
  line-height: 30px;
  text-align: center;
}

.nav-link.active {
  color: #b93a34;
}

.nav-link.dropdown:after {
  content: ">";
  display: inline-block;
  margin-left: 7px;
  transform: rotate(90deg) scale(0.8, 1.5);
}

.resources .title {
  color: #000000;
  font-size: 26px;
  font-weight: bold;
  letter-spacing: 0;
  line-height: 40px;
  margin-bottom: 25px;
  text-transform: uppercase;
}

.subTitle {
  color: #000000;
  font-size: 18px;
  letter-spacing: 0;
  line-height: 24.2px;
  margin-bottom: 40px;
  font-weight: 500;
}

.sideMenu {
  width: 145px;
  margin-right: 30px;
  text-transform: uppercase;
}
.sideMenu.fr {
  margin-right: 20px;
}
.sideMenu.fr a {
  font-size: 13px;
  padding: 20px 12px;
}

.sideMenu a {
  height: 55px;
  background-color: #f2f2f2;
  box-shadow: 0 0 2px 0 rgba(0, 0, 0, 0.36);
  color: #000 !important;
  font-size: 16px;
  font-weight: 600;
  letter-spacing: 0;
  line-height: 24.2px;
  display: flex;
  align-items: center;
  padding: 20px;
  cursor: pointer;
}

.sideMenu a.sub {
  background-color: #ffffff;
}

.sideMenu a.active {
  background-color: #212121;
  color: #fff !important;
  border: #b93a34 3px solid;
  box-shadow: none;
  cursor: auto;
  position: relative;
}
.sideMenu a.active:after {
  content: "";
  background: url(../images/active-arrow.png) no-repeat;
  background-size: cover;
  position: absolute;
  top: 50%;
  right: 0;
  transform: translate(50%, -50%);
  width: 20px;
  height: 20px;
}

.sideMenu-container {
  display: flex;
  justify-content: center;
  align-items: flex-start;
  max-width: calc(69.25em + 175px);
}

@media (max-width: 1350px) {
  .sideMenu-container, .container-sideMenu {
    padding: 0 30px;
  }
}
@media (max-width: 400px) {
  .sideMenu-container, .container-sideMenu {
    padding: 0 10px;
  }
}
.container-sideMenu {
  max-width: calc(69.25em + 175px);
  padding-left: 170px;
}
@media (max-width: 1350px) {
  .container-sideMenu {
    padding-left: 200px;
  }
}
@media (max-width: 767px) {
  .container-sideMenu {
    padding-left: 30px;
  }
}
@media (max-width: 400px) {
  .container-sideMenu {
    padding-left: 10px;
  }
}

.resources .logoBox {
  display: flex;
  align-items: center;
  justify-content: space-between;
  flex-wrap: wrap;
  margin-bottom: 20px;
}

.resources .logoBox:last-child {
  margin-bottom: 100px;
}

.resources .logoBox.multi {
  display: flex;
  align-items: flex-start;
  justify-content: space-between;
}
@media (max-width: 767px) {
  .resources .logoBox.multi {
    flex-direction: column;
  }
}

.resources .logoBox .logo {
  display: flex;
  justify-content: center;
  align-items: center;
  position: relative;
  margin-bottom: 40px;
}
.resources .logoBox .logo .ccs {
  width: 190px;
}

.resources .logoBox .logo:not(:last-child) {
  margin-right: 30px;
}

.resources .logoBox .logo img {
  max-height: 70px;
  max-width: 220px;
}

.resources .logoBox .logo.pubmed {
  justify-content: flex-start;
}

.resources .logoBox .logo.pubmed img {
  max-height: 106px;
  max-width: 106px;
}

.resources .logoBox .logo img:last-child {
  position: absolute;
  z-index: -1;
}

.resources .logoBox .logo:hover img:last-child {
  z-index: 1;
  cursor: pointer;
  width: 100%;
}

.home .about-container {
  background: white;
  margin-top: 60px;
  padding-top: 40px;
}

.home .about {
  display: flex;
  align-items: flex-start;
}

.home .about img {
  max-width: 180px;
  margin-right: 25px;
}

.resources {
  /* leaving site popup */
}
.resources #main {
  background-color: #ffffff;
}
.resources .sign-out {
  background-color: #ffffff;
  border: 10px solid #b9b9b9;
  border-radius: 20px;
  padding: 80px 50px;
  /* hide p and close x */
  /* override button */
}
.resources .sign-out h1 {
  font-size: 0px;
  text-align: center;
  /* switch text */
}
.resources .sign-out h1:after {
  font-size: 18px;
  font-weight: 500;
  line-height: 24.2px;
  letter-spacing: 0;
  color: black;
  text-transform: none;
  content: "You are now leaving the website of Janssen Inc. Links to all external sites are provided as a resource to our visitors. Janssen Inc. assumes no responsibility for the content of these sites. Janssen Inc. has no control over these sites and the opinions, claims or comments contained in these sites should not be attributed to Janssen Inc., unless otherwise specified.";
}
.resources .sign-out.fr h1:after {
  content: "Vous quittez maintenant le site Web de Janssen Inc. Les liens vers tous les sites externes sont fournis comme ressource à nos visiteurs. Janssen Inc. n’assume aucune responsabilité quant au contenu de ces sites. Janssen Inc. n’a aucun contrôle sur ces sites et les opinions, les allégations ou les commentaires contenus dans ces sites ne doivent pas être attribués à Janssen Inc., sauf indication contraire.";
}
.resources .sign-out.fr .leave-site-link:after {
  content: "Continuer";
}
.resources .sign-out.fr .closeLeaveSitePopup:after {
  content: "Retour";
}
.resources .sign-out ul {
  margin: 40px auto 0;
  max-width: 370px;
}
.resources .sign-out .closeicon,
.resources .sign-out p {
  display: none;
}
.resources .sign-out .closeLeaveSitePopup {
  font-size: 0;
}
.resources .sign-out .closeLeaveSitePopup:after {
  color: #535353;
  opacity: 0.5;
  font-size: 22px;
  font-weight: bold;
  letter-spacing: 0;
  line-height: 30px;
  content: "Return";
}
.resources .sign-out .leave-site-link {
  font-size: 0px;
}
.resources .sign-out .leave-site-link:after {
  color: #b93a34;
  font-size: 22px;
  font-weight: bold;
  letter-spacing: 0;
  line-height: 30px;
  content: "Continue";
}

.toTop {
  position: fixed;
  right: 40px;
  bottom: 100px;
  max-width: 48px;
  cursor: pointer;
  border: none;
  background: transparent;
}

.printBtn {
  position: absolute;
  max-width: 40px;
  top: 50%;
  right: 0px;
  transform: translateY(-50%);
}

.dropdown {
  position: relative;
}

.dropdownMenu {
  position: absolute;
  width: 100%;
  min-width: 170px;
  margin-top: 5%;
  top: 90%;
  left: 50%;
  transform: translateX(-50%);
  background-color: white;
  font-size: 16px;
  font-weight: 600;
  letter-spacing: 0;
  line-height: 24.2px;
  padding: 6px 10px;
  box-shadow: 0 0 2px 0 rgba(0, 0, 0, 0.36);
  z-index: 999;
  display: none;
}

.dropdownMenu a {
  padding: 6px;
  color: #777;
  display: block;
  text-transform: uppercase;
}

.dropdownMenu a:not(:last-child) {
  border-bottom: 1px solid #ddd;
}

.dropdownMenu a:hover {
  color: #111;
}

.dropdown:hover .dropdownMenu {
  display: block;
}

/* responsive update  */
@media (min-width: 768px) {
  .hamburger-menu {
    display: none !important;
  }
}
@media (max-width: 767px) {
  .open_menu {
    overflow: hidden;
  }

  .header-logo {
    left: -8px;
    width: 11.5em;
  }

  .navbar {
    height: 95px;
  }
  .navbar li {
    display: none;
  }
  .navbar + figure {
    background: #D8D8D8;
    min-height: 50px;
    display: flex;
    align-items: flex-end;
  }

  .stick_header .header-middle figure {
    display: none;
  }
  .stick_header .header-middle .navbar {
    height: 114px;
  }

  .menu {
    display: block;
    left: initial;
    right: 30px;
    top: 25px;
    cursor: pointer;
    height: 40px;
    background: transparent;
    border: none;
    outline: none !important;
  }
  .menu span {
    background: black;
    height: 4px;
  }

  .hamburger-menu {
    width: 100%;
    height: 100vh;
    position: initial;
    padding-left: 0px;
    padding-right: 0px;
    background: white;
    overflow-y: auto;
  }
  .hamburger-menu .navbar {
    background: white;
    height: 100%;
    margin-top: 130px;
    padding: 0px;
  }
  .hamburger-menu .navbar li {
    display: block;
  }
  .hamburger-menu .navbar li a {
    margin: 0;
  }
  .hamburger-menu .navbar li:nth-child(2), .hamburger-menu .navbar li:nth-child(3) {
    position: relative;
  }
  .hamburger-menu .navbar li:nth-child(2)::before, .hamburger-menu .navbar li:nth-child(3)::before {
    content: "";
    width: 100%;
    height: 100%;
    position: absolute;
    top: 0;
    left: 0;
    z-index: 999;
    cursor: pointer;
  }
  .hamburger-menu .navbar li:nth-child(2):active::before, .hamburger-menu .navbar li:nth-child(2):focus::before, .hamburger-menu .navbar li:nth-child(2):focus-within::before, .hamburger-menu .navbar li:nth-child(2):hover::before, .hamburger-menu .navbar li:nth-child(3):active::before, .hamburger-menu .navbar li:nth-child(3):focus::before, .hamburger-menu .navbar li:nth-child(3):focus-within::before, .hamburger-menu .navbar li:nth-child(3):hover::before {
    height: 66px;
  }
  .hamburger-menu .navbar li:nth-child(2):active .dropdown .dropdownMenu, .hamburger-menu .navbar li:nth-child(2):focus .dropdown .dropdownMenu, .hamburger-menu .navbar li:nth-child(2):focus-within .dropdown .dropdownMenu, .hamburger-menu .navbar li:nth-child(2):hover .dropdown .dropdownMenu, .hamburger-menu .navbar li:nth-child(3):active .dropdown .dropdownMenu, .hamburger-menu .navbar li:nth-child(3):focus .dropdown .dropdownMenu, .hamburger-menu .navbar li:nth-child(3):focus-within .dropdown .dropdownMenu, .hamburger-menu .navbar li:nth-child(3):hover .dropdown .dropdownMenu {
    display: block;
  }
  .hamburger-menu .navbar .nav-link {
    font-size: 28px;
    font-weight: 500;
    letter-spacing: 0;
    line-height: 50px;
    text-align: center;
  }
  .hamburger-menu .navbar .nav-link.active {
    background: black;
    color: white;
    width: 100%;
  }
  .hamburger-menu .navbar .nav-link.dropdown .dropdownMenu {
    position: initial;
    transform: none;
    box-shadow: none;
    background-color: black;
    font-size: 16px;
    font-weight: 500;
    letter-spacing: 0;
    line-height: 24.2px;
    margin-left: -16px;
    margin-right: -16px;
    width: calc(100% + 32px);
    margin-top: 0px;
  }
  .hamburger-menu .navbar .nav-link.dropdown .dropdownMenu a {
    border-bottom: 0px;
    color: white;
    background-color: black;
    margin-top: 15px;
    text-transform: capitalize;
  }
  .hamburger-menu .navbar .nav-link.dropdown .dropdownMenu a.active {
    display: inline-block;
    border-top: 2px solid #B93A34;
    border-bottom: 2px solid #B93A34;
  }
  .hamburger-menu .navbar .nav-link.dropdown:hover .dropdownMenu {
    display: none;
  }
  .hamburger-menu .navbar .nav-link.dropdown:after {
    display: none;
  }

  .sideMenu {
    display: none;
  }

  .toTop {
    right: 4%;
    bottom: 4%;
    max-width: 30px;
  }

  .resources .logoBox {
    flex-wrap: nowrap;
    overflow-x: auto;
  }
  .resources .logoBox::-webkit-scrollbar {
    height: 8px;
  }
  .resources .logoBox::-webkit-scrollbar-track {
    background-color: #EFEFEF;
    border-radius: 6px;
  }
  .resources .logoBox::-webkit-scrollbar-thumb {
    border-radius: 6px;
    background-color: #a7a7a7;
  }

  .home .d-flex.justify-content-center {
    flex-direction: column;
  }
  .home .category:not(first-child) {
    margin-top: 30px;
  }
  .home .title {
    font-size: 20px;
    font-weight: bold;
    letter-spacing: 0;
    line-height: 40px;
  }
  .home .about {
    flex-direction: column;
  }
  .home .about img {
    margin-bottom: 30px;
  }

  .printBtn {
    display: none;
  }

  #zoomImg, #zoomTable {
    display: none;
  }

  .section.wsubhead a {
    display: none !important;
  }

  .wsubhead + .subhead {
    margin-left: 0px;
  }

  .hide-mbl {
    display: none !important;
  }

  .treatment-table3 h2 a {
    margin-right: 0px;
  }

  .treatment-firstline h2 a {
    display: none;
  }
}
.treatment-firstline h2 {
  padding-left: 55px !important;
  position: relative;
}
.treatment-firstline h2 a {
  position: absolute;
  left: 0px;
  top: 6px;
}
@media (max-width: 991px) {
  .treatment-firstline h2 {
    line-height: 1.1625em !important;
  }
  .treatment-firstline h2 a {
    top: -5px;
  }
}
@media (max-width: 767px) {
  .treatment-firstline h2 {
    padding-left: 0px !important;
  }
}

.red-table {
  font-size: 1em;
  color: black;
  font-family: "Karbon";
}
.red-table--row {
  display: flex;
}
.red-table--row:nth-child(2) > div {
  border-top-left-radius: 5px;
}
.red-table--row:last-child > div:first-child {
  border-bottom-left-radius: 5px;
  border-bottom: none;
}
.red-table--row > div {
  width: 80%;
}
.red-table--row > div:first-child {
  background: #b83934;
  color: white;
  text-transform: uppercase;
  font-weight: 700;
  width: 20%;
  padding: 15px;
  border-bottom: 3px solid white;
}
.red-table--row > div:nth-child(2) {
  border-bottom: 3px solid #b83934;
  padding: 0px;
}
.red-table--row ul {
  padding: 15px;
  list-style: disc;
  line-height: 1.4em;
  color: black;
}
.red-table--row ul li {
  margin-left: 15px;
}
.red-table--row ul li ul {
  padding: 0px;
}
.red-table--row ul li ul li {
  display: flex;
  margin-left: 0px;
}
.red-table--row ul li ul li:before {
  content: "-";
  transform: scaleX(1.5);
  margin-right: 6px;
}
.red-table--row ul li ul li sup {
  top: 0.7em;
}
.red-table .red-table--top {
  display: flex;
}
.red-table .red-table--top > div {
  width: 40%;
  padding: 15px;
}
.red-table .red-table--top > div:nth-child(1) {
  width: 20%;
  background: white;
}
.red-table .red-table--top > div:nth-child(2) {
  background: #b83934;
  color: white;
  text-transform: uppercase;
  border-top-left-radius: 5px;
  font-weight: 700;
}
.red-table .red-table--top > div:nth-child(2).full {
  width: 80%;
  border-top-right-radius: 5px;
}
.red-table .red-table--top > div:nth-child(3) {
  background: #b83934;
  color: white;
  text-transform: uppercase;
  border-top-right-radius: 5px;
  font-weight: 700;
}
.red-table .row-1 {
  padding: 15px;
}
.red-table .row-2 {
  display: flex;
}
.red-table .row-2 > * {
  width: 50%;
  color: black;
  padding: 15px;
  line-height: 1.4em;
}
.red-table .row-2 .red-table--subHeader {
  text-align: left;
}
.red-table--subHeader {
  color: black;
  font-weight: 700;
  text-align: center;
  padding: 15px;
  background-color: #f1d7d6;
}
.red-table .bg-grey {
  background-color: #eeeeed;
}
.red-table .bg-darkGrey {
  background-color: #b9b9b9;
}

body .references ul {
  margin-bottom: 65px;
}
body .references ul li a, body .references ul li:nth-child(2) a, body .references .references-main > a {
  height: 100%;
  width: 100%;
  max-width: 400px;
  padding: 12px;
  display: block;
  margin-bottom: 0px;
  display: flex;
  justify-content: center;
  align-items: center;
  padding-left: 50px;
  padding-right: 50px;
}
body .references .references-main > a {
  margin-bottom: 65px;
}
body .references li:nth-child(1) a:before {
  left: 16px;
}
body .references li:nth-child(2) a:before {
  right: 16px;
}
@media (max-width: 575px) {
  body .references {
    margin-bottom: 45px;
  }
  body .references .col-sm-6.col-12 {
    margin-bottom: 15px;
  }
  body .references li a, body .references li:nth-child(2) a {
    max-width: 100%;
  }
}
body .references .ref a {
  color: #000000;
  text-decoration: underline !important;
}

.preffered-m {
  display: none !important;
}

.preffered-d {
  display: flex !important;
}

@media (max-width: 1500px) {
  .break-1500 .preffered-left {
    width: 100%;
  }
  .break-1500 .preffered-left-top {
    border-radius: 5px;
  }
  .break-1500 .preffered-right {
    width: 100%;
    padding: 20px 0 0;
  }
  .break-1500 .preffered-right-top {
    border-radius: 5px;
  }
  .break-1500 .preffered-right-btm {
    border-left: 0;
  }
  .break-1500 .preffered-col1 p.work:before, .break-1500 .preffered-col1 p.work:after {
    display: none;
  }
}

@media (max-width: 480px) {
  .waldenstroms h1 {
    font-size: 1.7em;
  }
}
@media (max-width: 400px) {
  .redSubHead, .testing h3 {
    font-size: 1.34em;
  }

  .additional-tests h2, .to-treat h2 {
    font-size: 1.8em !important;
  }

  .font-sm-on-mobile {
    font-size: 90%;
  }

  .to-treat p .font-sm-on-mobile {
    color: black;
    font-weight: initial;
  }

  .table-striped {
    font-size: 0.7em !important;
  }

  .waldenstroms h1 {
    font-size: 1.3em;
  }

  .waldenstroms h2 {
    font-size: 1.2em;
  }
}
.macro {
  color: black !important;
  font-weight: 400 !important;
}

.font-sm {
  font-size: 1em !important;
}

.resources-footnote {
  font-size: 1em;
  color: black;
  margin: 30px 0 60px;
}

.resources-link {
  color: #565656;
}
.resources-link:hover {
  color: #333;
}

/*# sourceMappingURL=style-update.css.map */